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A variety of non-pharmacological approaches
for treatment of cognitive, functional and behavioural symptoms
in AD have been examined. In a meta-analysis of 17 controlled
trials of cognitive training interventions, benefits were noted
on measures of learning, memory, executive function and activities
of daily living (ADLs) (Sitzer et al ). Further evidence
of long-term benefits of cognitive training was demonstrated
in an RCT of elderly, nondemented subjects (Willis et al
). Subjects demonstrated improved cognitive abilities and less
functional decline, even five years after initiation of treatment.
In an RCT of nursing home residents with AD, a simple exercise
program was also associated with slower declines in ADLs (Rolland
et al ).
Cognitive training in Alzheimer’s
disease: a meta-analysis of the literature
(Acta Psychiatr Scand 2006;114:75-90)
d.i. Sitzer,
e.w. Twamley,
d.v. Jeste
San Diego, CA
Long-term effects of cognitive training
on everyday functional outcomes in older adults
(JAMA 2006;296:2805-2814)
s.l. Willis,
s.l. Tennstedt,
m. Marsiske,
k. Ball,
et al
State College, PA
Exercise program for nursing home
residents with Alzheimer’s disease: a 1-year randomized,
controlled trial
(J Am Geriatr Soc 2007;55:158-165)
y. Rolland,
f. Pillard,
a. Klapouszczak,
e. Reynish,
et al
Toulouse, France
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