IN THIS ISSUE NOVEMBER 2006

CANADIAN CONTRIBUTIONS TO THE LITERATURE

  • Many cognitive impairment syndromes may progress to AD
  • Symptom checklist after donepezil reveals different responses to those of clinicians
  • Memantine treatment had the most impact on moderate-severe AD patients

MILD COGNITIVE IMPAIRMENT

  • Over 50% of people with MCI progress to dementia within five years
  • Cognitively impaired people should be followed closely for progression to dementia

BODY WEIGHT AND COGNITIVE IMPAIRMENT

  • BMI is associated with cognitive function
  • Weight loss is often seen before the development of AD

CJD and NEUROPSYCHIATRIC SYMPTOMS

  • Neuropsychiatric symptoms are prevalent in sCJD

DEPRESSION AS A RISK FACTOR FOR COGNITIVE DISORDERS

  • Depression was associated with increased risk of MCI
  • A history of depression may infer future AD

ChEIS’ EFFECTS ON NEUROPSYCHIATRIC SYMPTOMS

  • Donepezil reduced behavioural symptoms in AD patients

VAGUS NERVE STIMULATION AND AD

  • Long-term tolerability was shown in patients with AD
 

 

 

 

 

 

 

 
 
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