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CANADIAN CONTRIBUTIONS
TO THE LITERATURE
- Many cognitive impairment syndromes may
progress to AD
- Symptom checklist after donepezil reveals
different responses to those of clinicians
- Memantine treatment had the most impact
on moderate-severe AD patients
MILD COGNITIVE IMPAIRMENT
- Over 50% of people with MCI progress to
dementia within five years
- Cognitively impaired people should be followed
closely for progression to dementia
BODY WEIGHT AND
COGNITIVE IMPAIRMENT
- BMI is associated with cognitive function
- Weight loss is often seen before the development
of AD
CJD and NEUROPSYCHIATRIC
SYMPTOMS
- Neuropsychiatric symptoms are prevalent
in sCJD
DEPRESSION AS
A RISK FACTOR FOR COGNITIVE DISORDERS
- Depression was associated with increased
risk of MCI
- A history of depression may infer future
AD
ChEIS’ EFFECTS
ON NEUROPSYCHIATRIC SYMPTOMS
- Donepezil reduced behavioural symptoms
in AD patients
VAGUS NERVE STIMULATION
AND AD
- Long-term tolerability was shown in patients
with AD
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