More evidence is now available on controllable
vascular risk factors: cerebral emboli (Purandare et al
), hypercholesterolemia (Green et al ) and hypertension/obesity/diabetes
(Hayden et al ). These studies support currently available
strategies to prevent Alzheimer’s disease and vascular dementia
for all individuals. They require regular visits to a primary
care practitioner and compliance towards recommendations for changes
in lifestyle and, if necessary, medications.
Cerebral emboli as a potential cause
of Alzheimer’s disease
and vascular dementia: case-control study
(BMJ, DOI:10.1136/BMJ.38814.696493.AE
April 28, 2006)
NITIN PURANDARE,
ALISTAIR BURNS,
KEVIN J. DALY,
JAYNE HARDICRE,
ET AL,
manchester, uk
Statin use and the risk of Alzheimer’s
disease: The MIRAGE Study
(ALZHEIMER’S & DEMENTIA
2006;2:96-103)
ROBERT C. GREEN,
SALLY E. MCNAGNY,
PARIMALA JAYAKUMAR,
L. ADRIENNE CUPPLES,
ET AL
BOSTON, MA,
REDWOOD, CA
for the mirage study group
Vascular risk factors for incident
Alzheimer disease and vascular dementia: The Cache County Study
(ALZHEIMER DIS ASSOC DISORD 2006;20:93-100)
KATHLEEN M. HAYDEN, PhD,
PETER P. ZANDI, PhD,
CONSTANTINE G. LYKETSOS, MD,
ARA S. KHACHATURIAN, PhD,
ET AL,
various centres, usa
for the cache county investigators
|
